Insulin Synthesis Methods and Modifications
Proteolysis of insulin in the endoplasmic reticulum followed by cleavage of the C chain of pro-insulin to form insulin is a good example of posttranslational modification. This paper looks at the insulin molecule, with a particular reference to its primary, secondary, tertiary and quaternary structures. Features of the protein which enable the molecule to perform its biochemical functions are also considered as are the posttranslational modifications and cellular activity. Structurally, insulin...
